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Takashi Nakamura Selected Research

Hyperuricemia

1/2024Seasonal variations for newly prescribed urate-lowering drugs for asymptomatic hyperuricemia and gout in Japan.
10/2023Overnight changes in uric acid, xanthine oxidoreductase and oxidative stress levels and their relationships with sleep-disordered breathing in patients with coronary artery disease.
1/2022The reality of treatment for hyperuricemia and gout in Japan: A historical cohort study using health insurance claims data.
9/2021Independent association of plasma xanthine oxidoreductase activity with hypertension in nondiabetic subjects not using medication.
10/2020Plasma xanthine oxidoreductase (XOR) activity in patients who require cardiovascular intensive care.
7/2020Differential regulation of hypoxanthine and xanthine by obesity in a general population.
1/2020ABCG2 expression and uric acid metabolism of the intestine in hyperuricemia model rat.
9/2019Annual change in plasma xanthine oxidoreductase activity is associated with changes in liver enzymes and body weight.
2/2018Elevated serum uric acid level was a notable adverse event during combination therapy with sofosbuvir and ribavirin.

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Takashi Nakamura Research Topics

Disease

75Neoplasms (Cancer)
05/2024 - 01/2002
17Rheumatoid Arthritis
01/2017 - 08/2004
14Neoplasm Metastasis (Metastasis)
03/2024 - 08/2002
14Inflammation (Inflammations)
05/2023 - 08/2004
12Insulin Resistance
01/2022 - 04/2003
12Osteoarthritis
03/2016 - 11/2002
11Bone Resorption
02/2024 - 04/2002
10Heart Failure
01/2023 - 06/2012
9Osteoporosis
02/2024 - 01/2003
9Hyperuricemia
01/2024 - 02/2018
9Liver Diseases (Liver Disease)
05/2023 - 11/2018
9Hypertrophy
01/2023 - 01/2006
9Obesity
09/2022 - 05/2018
8Melanoma (Melanoma, Malignant)
03/2024 - 03/2002
8Cardiovascular Diseases (Cardiovascular Disease)
02/2023 - 02/2008
8Pain (Aches)
01/2023 - 01/2002
8Type 2 Diabetes Mellitus (MODY)
11/2022 - 01/2017
8Body Weight (Weight, Body)
01/2021 - 02/2002
7Bites and Stings (Sting)
03/2024 - 06/2014
7Atherosclerosis
10/2023 - 09/2002
7Fibrosis (Cirrhosis)
05/2022 - 05/2007
7Infections
07/2021 - 03/2003
7Urinary Bladder Neoplasms (Bladder Cancer)
12/2018 - 06/2011
6Coronary Artery Disease (Coronary Atherosclerosis)
10/2023 - 01/2021
6Osteonecrosis (Kienbock's Disease)
03/2022 - 08/2003
6Chronic Renal Insufficiency
09/2021 - 08/2007
6Stomach Neoplasms (Stomach Cancer)
07/2019 - 03/2002
6Arthritis (Polyarthritis)
04/2012 - 09/2002
5Ischemia
12/2023 - 03/2002
5Hypoxia (Hypoxemia)
11/2023 - 01/2010
5Breast Neoplasms (Breast Cancer)
04/2021 - 09/2002
5Carcinoma (Carcinomatosis)
01/2017 - 01/2003
5Knee Osteoarthritis
10/2015 - 04/2007
5Spinal Cord Diseases
02/2012 - 01/2002
5Synovial Sarcoma (Synovioma)
09/2008 - 10/2002
4Thrombosis (Thrombus)
12/2023 - 01/2003
4Hypertension (High Blood Pressure)
02/2023 - 05/2014
4Dyskinesias (Dyskinesia)
01/2023 - 01/2021
4Fatigue
05/2022 - 05/2004
4Albuminuria
09/2021 - 03/2016
4Diabetes Mellitus
08/2021 - 01/2017
4Lymphatic Metastasis
04/2021 - 06/2002
4Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2021 - 08/2004
4Colitis
02/2017 - 08/2015
3COVID-19
05/2024 - 10/2021
3Heart Arrest (Cardiac Arrest)
01/2024 - 05/2012
3Type 1 Diabetes Mellitus (Autoimmune Diabetes)
02/2023 - 09/2013
3Parkinson Disease (Parkinson's Disease)
01/2023 - 01/2021

Drug/Important Bio-Agent (IBA)

38Xanthine DehydrogenaseIBA
01/2024 - 06/2016
18Proteins (Proteins, Gene)FDA Link
01/2023 - 06/2002
17Uric Acid (Urate)IBA
01/2024 - 06/2016
15LipidsIBA
10/2023 - 11/2002
11Lipid NanoparticlesIBA
05/2024 - 01/2016
11CytokinesIBA
01/2020 - 01/2002
10Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2010
9Messenger RNA (mRNA)IBA
05/2024 - 03/2002
9AntigensIBA
05/2024 - 08/2009
9Glucose (Dextrose)FDA LinkGeneric
01/2021 - 01/2006
8XanthineIBA
10/2023 - 01/2019
8EnzymesIBA
01/2023 - 02/2007
8Small Interfering RNA (siRNA)IBA
05/2022 - 07/2015
7FYX-051IBA
02/2023 - 06/2016
7Reactive Oxygen Species (Oxygen Radicals)IBA
02/2023 - 01/2018
7LigandsIBA
01/2022 - 04/2006
7Liposomes (Liposome)IBA
01/2022 - 06/2011
6InterferonsIBA
03/2024 - 06/2014
6CollagenIBA
08/2021 - 07/2002
5Therapeutic UsesIBA
03/2024 - 04/2005
5Alanine Transaminase (SGPT)IBA
05/2023 - 08/2004
5Indicators and Reagents (Reagents)IBA
01/2023 - 09/2002
5Levodopa (L Dopa)FDA LinkGeneric
01/2023 - 09/2019
5Transcription Factors (Transcription Factor)IBA
01/2020 - 12/2006
5Heparin (Liquaemin)FDA LinkGeneric
04/2016 - 04/2004
5Interleukin-6 (Interleukin 6)IBA
08/2015 - 01/2002
4HypoxanthineIBA
10/2023 - 07/2020
4purineIBA
05/2023 - 02/2017
4HDL CholesterolIBA
09/2022 - 01/2018
4Insulin (Novolin)FDA Link
12/2021 - 01/2016
4Immune Checkpoint InhibitorsIBA
01/2021 - 01/2018
4Triglycerides (Triacylglycerol)IBA
01/2020 - 04/2003
4AdiponectinIBA
01/2020 - 01/2017
4CreatinineIBA
01/2020 - 08/2007
4SteroidsIBA
12/2018 - 08/2003
4Cell Wall SkeletonIBA
01/2016 - 06/2011
4LectinsIBA
04/2012 - 09/2002
4Oxidized LDL ReceptorsIBA
04/2012 - 09/2002
4Hyaluronic Acid (Hyaluronan)IBA
03/2012 - 01/2007
3RNA (Ribonucleic Acid)IBA
05/2023 - 07/2003

Therapy/Procedure

50Therapeutics
03/2024 - 03/2002
26Immunotherapy
05/2024 - 03/2011
7Osteotomy
01/2019 - 01/2007
6Transplantation
03/2022 - 08/2003
6Drug Therapy (Chemotherapy)
07/2019 - 07/2002
5Conservative Treatment
01/2021 - 01/2002
5Aftercare (After-Treatment)
11/2017 - 04/2003
5Radiotherapy
11/2012 - 01/2005
4Glycemic Control
08/2021 - 03/2016
4Laminoplasty
02/2012 - 09/2006
3Critical Care (Surgical Intensive Care)
01/2023 - 04/2019
3Percutaneous Coronary Intervention
02/2022 - 01/2021